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A man tries to live a normal life despite the fact that he sometimes turns into a sheepdog.

Re-formed by a coded message to their web site, a group of animal rights activists set off to free an imprisoned colleague from a terrifying ordeal. Their rescue mission leads them to a disused lab, but what should have been a simple raid turns into a series of twisted and mind bending incidents where the free and the caged switch places, in this tormented psychological horror.

An unknown and lethal virus has wiped out five billion people in 1996. Only 1% of the population has survived by the year 2035, and is forced to live underground. A convict (James Cole) reluctantly volunteers to be sent back in time to 1996 to gather information about the origin of the epidemic (who he’s told was spread by a mysterious “Army of the Twelve Monkeys”) and locate the virus before it mutates so that scientists can study it. Unfortunately Cole is mistakenly sent to 1990, six years earlier than expected, and is arrested and locked up in a mental institution, where he meets Dr. Kathryn Railly, a psychiatrist, and Jeffrey Goines, the insane son of a famous scientist and virus expert.

Sassy postgrad Elle Woods (Witherspoon) is all about animal rights. In fact, she puts her nuptial plans on hold to head to Washington D.C. to get an anti-animal testing bill passed. Her building’s doorman (Newhart) quickly shows her the ways and workings of our nation’s capital.

A powerful virus escapes from a British research facility. Transmitted in a drop of blood and devastating within seconds, the virus locks those infected into a permanent state of murderous rage. Within 28 days the country is overwhelmed and a handful of survivors begin their attempts to salvage a future, little realising that the deadly virus is not the only thing that threatens them.