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Two men wake up at opposite sides of a dirty, disused bathroom, chained by their ankles to pipes. Between them lies a dead man loosely clutching a hand-held tape player and a handgun. Each finds a tape the perfect fit for the player in their back pocket. They play the tapes. One is threatened, the other isn’t. But they have a task: One must kill the other by 6:00, or his wife and daughter will die. They find hacksaws in a toilet, and try to cut the chains, but it doesn’t work. They are the two newest victims of the Jigsaw Killer. In a flashback, we learn of Amanda, a girl who falls victim to the Jigsaw Killer. On her head is a mask, which is hooked into her lower jaw. There is a timer on it. Only one key will unlock it, and that key is in the digestive tract of her cell mate who lies paralyzed on the opposite side of the room. If she doesn’t unlock the mask in time, her lower jaw will be ripped wide open. She survives, but her cell mate doesn’t. Through a series of flashbacks, we learn of more victims, and of the nearly-successful capture of the Jigsaw Killer, who doesn’t actually kill his victims. Instead, he finds ways to make them kill either themselves, or each other, and he thinks the entire ‘game’ out perfectly, with no other ways out. Or so it would seem.

FBI Agent Will Graham has been called out of early retirement to catch a serial killer, known by authorities as “The Tooth Fairy”. He asks for the help of his arch-nemesis, Dr. Hannibal “The Cannibal” Lecter, so that he can be able to catch “The Tooth Fairy” and bring him to justice. The only problem is that “The Tooth Fairy” is getting inside information about Graham and his family from none other than Dr. Lecter.

In the not-so-far future the polar ice caps have melted and the resulting raise of the ocean waters has drowned all the coastal cities of the world. Withdrawn to the interior of the continents, the human race keeps advancing, reaching to the point of creating realistic robots (called mechas) to serve him. One of the mecha-producing companies builds David, an artificial kid which is the first to have real feelings, especially a never-ending love for his “mother”, Monica. Monica is the woman who adopted him as a substitute for her real son, who remains in cryo-stasis, stricken by an incurable disease. David is living happily with Monica and her husband, but when their real son returns home after a cure is discovered, his life changes dramatically. A futuristic adaptation of the tale of Pinocchio, with David being the “fake” boy who desperately wants to become “real”.