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When the murdered body of a young woman who works in the White House is found. Homicide detective Harlan Regis is called in. Upon arriving Senior Secret Service Agent Spikings objects to his presence, but he has the support of the National Security Adviser. Preliminary investigation suggests that it might be a sex crime. And Regis learns that the President’s son has a history of similar acts. He tries to get more info but Spikings’ impeding him but he is determined to find out what happened. Secret Service Agent Nina Chance tries to help him.

When student Jake Lo witnesses a killing, he finds himself caught between two feuding drug lords. Betrayed and set up by the federal agents protecting him, the only one he can trust is Ryan, a single-minded Chicago cop who reminds Jake of his deceased father. To clear his name, Jake agrees to help Ryan bring down the drug lords.

In New York, the ambitious Dr. Jack Byron and his associate Gordon Mitchell present the research of his assistant Sam Rogers to the CEO and board of directors of a corporation to sponsor a scientific expedition to Borneo. The objective is to find a flower, Blood Orchid, that flourishes for a couple of weeks every seven years and could be a fountain of youth, prolonging the expectation of life of human beings. They are succeeded and once in Borneo, they realize that it is the raining season and there is no boat available to navigate on the river. They pay US$ 50,000.00 to convince Captain Bill Johnson and his partner Tran to sail to the location. After an accident in a waterfall, the survivors realize that a pack of anacondas have gathered for mating and their nest is nearby the plantation of Blood Orchid, which made them bigger and bigger.